Target

Gene symbol :  
Cd33
NCBI gene ID :  
12489
Gene full name :  
CD33 molecule
Synonym :  
Siglec-3, GP67

Protein function

Protein name :  
CD33
Sialic acid-binding Ig-like lectin expressed on myeloid cells; modulates immune response.

Expected phenotype

Altered myeloid function

Human disease relevance

Target in myeloid malignancies (e.g. AML)

Model applications

Myeloid cell targeting, immunotherapy

Keywords:

Siglec, Myeloid, AML target

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Cd33

conditional Knockout Mouse

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