Target

Gene symbol :  
Dctn1
NCBI gene ID :  
13191
Gene full name :  
Dynactin subunit 1
Synonym :  
p150-glued, DCTN1

Protein function

Protein name :  
DCTN1
Anchors cytoplasmic dynein to cargo, essential for microtubule-based transport and mitosis.

Expected phenotype

Neuronal transport defects

Human disease relevance

Mutations linked to ALS and Perry syndrome

Model applications

Axonal transport, neurodegeneration

Keywords:

Dynactin, Microtubules, Neuron

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Dctn1

conditional Knockout mouse

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hPD-1
hLAG3

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hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.