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Conditional Knockout mice
Ece1

Ece1 conditional Knockout mouse

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Target

Gene symbol :  
Ece1
NCBI gene ID :  
230857
Gene full name :  
Endothelin converting enzyme 1
Synonym :  
Endothelin converting enzyme 1

Protein function

Protein name :  
ECE1
Converts inactive endothelin precursors to active peptides involved in vasoconstriction and development.

Expected phenotype

Cardiovascular and craniofacial anomalies

Human disease relevance

Linked to Hirschsprung disease and hypertension

Model applications

Cardiovascular biology, neural crest development

Keywords:

Endothelin, Vasoregulation, Neural crest

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Ece1

conditional Knockout mouse

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