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Conditional Knockout mice
Entpd1

Entpd1 conditional Knockout mouse

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Target

Gene symbol :  
Entpd1
NCBI gene ID :  
12495
Gene full name :  
Ectonucleoside triphosphate diphosphohydrolase 1
Synonym :  
Cd39

Protein function

Protein name :  
CD39
Degrades extracellular ATP and ADP to AMP; regulates purinergic signaling and inflammation.

Expected phenotype

Altered inflammation and immune regulation

Human disease relevance

Target in immunotherapy and thrombosis

Model applications

Immunosuppression, Treg function, inflammation

Keywords:

ATP metabolism, Tregs, Immunotherapy

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Entpd1

conditional Knockout mouse

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hPD-1
hLAG3

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hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.