Target

Gene symbol :  
Grn
NCBI gene ID :  
14824
Gene full name :  
Granulin precursor
Synonym :  
Granulin

Protein function

Protein name :  
Progranulin
Growth factor involved in wound repair, inflammation, and neurodegeneration.

Expected phenotype

Neurodegeneration, immune dysregulation

Human disease relevance

Linked to frontotemporal dementia (FTD)

Model applications

Neuroinflammation, FTD modeling, wound healing

Keywords:

Progranulin, FTD, Inflammation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Grn

conditional Knockout Mouse

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