Target

Gene symbol :  
Jchain
NCBI gene ID :  
16069
Gene full name :  
Joining chain of multimeric IgA and IgM
Synonym :  
IgJ

Protein function

Protein name :  
J chain
Facilitates polymerization of IgA and IgM for mucosal immunity.

Expected phenotype

Impaired mucosal antibody function

Human disease relevance

Associated with immune deficiencies

Model applications

Mucosal immunity, antibody secretion

Keywords:

IgA, IgM, B-cell function

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Jchain

conditional Knockout Mouse

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