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Applications of the genO‑hSTING mouse model
Broad range of applications in the fields of immuno-oncology, immuno-inflammation and autoimmunity:
- Assess the efficacy of STING-targeting small molecule compounds
- Perform tumor inhibition assays
- Test compounds for the inhibition of inflammatory responses
- Investigate the mode of action (MoA) of various compounds and understand their therapeutic potential
Features
- Physiological regulation of the human STING
- Fully functional mouse immune system
- Lack of expression of the murine target gene
- Different versions of genO‑hSTING models are available:
Clients
