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Conditional Knockout mice
Hprt

Hprt conditional Knockout mouse

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Target

Gene symbol :  
Hprt
NCBI gene ID :  
15452
Gene full name :  
Hypoxanthine Phosphoribosyltransferase 1
Synonym :  
Hprt1

Protein function

Protein name :  
HPRT1
Enzyme in purine salvage pathway; converts hypoxanthine to IMP.

Expected phenotype

Neurological dysfunctions, hyperuricemia

Human disease relevance

Mutations cause Lesch-Nyhan syndrome.

Model applications

Purine metabolism and neurological disorder models

Keywords:

Purine metabolism, Neurology, Lesch-Nyhan

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Hprt

conditional Knockout mouse

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hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.