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Conditional Knockout mice
Sh3pxd2a

Sh3pxd2a conditional Knockout mouse

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Target

Gene symbol :  
Sh3pxd2a
NCBI gene ID :  
14218
Gene full name :  
SH3 and PX domains 2A
Synonym :  
Tks5, Fish

Protein function

Protein name :  
SH3PXD2A
Scaffold protein regulating podosome formation and cell invasion.

Expected phenotype

Reduced podosome formation, defective invasion

Human disease relevance

Involved in cancer metastasis

Model applications

Invasion biology, actin remodeling

Keywords:

Tks5, Podosome, Cell migration

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Sh3pxd2a

conditional Knockout mouse

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hPD-1
hLAG3

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hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.