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Conditional Knockout mice
Wdr45

Wdr45 conditional Knockout mouse

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Target

Gene symbol :  
Wdr45
NCBI gene ID :  
54636
Gene full name :  
WD repeat domain 45
Synonym :  
WIPI4

Protein function

Protein name :  
WDR45
Regulates autophagy via phosphoinositide binding and trafficking.

Expected phenotype

Neurodegeneration, motor defects

Human disease relevance

Causes BPAN (beta-propeller protein-associated neurodegeneration)

Model applications

Autophagy, neurodegeneration

Keywords:

WIPI family, Autophagy, BPAN

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Wdr45

conditional Knockout mouse

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hPD-1
hLAG3

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hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.