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Applications of the genO‑hCCR8/hCCL1 mouse model
Useful applications for researchers working on different biomedical fields, such as immuno-oncology:
- Assess the efficacy of CCR8 and/or CCL1-targeting therapeutics
- Perform tumor growth inhibition assays in the context of monotherapies or combotherapies
- Investigate the mode of action (MoA) of various compounds and understand their therapeutic potential
Features
- Physiological regulation and expression pattern of human CCR8 and human CCL1
- Functional CCR8/CCL1 signaling axis
- Fully functional mouse immune system
- Lack of expression of the murine target genes
Clients
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