BTK conditional Knockout mouse

Target

Gene symbol :

BTK

NCBI gene ID :

12142

Gene full name :

Bruton's tyrosine kinase

Synonym :

Bruton's tyrosine kinase

Protein function

Protein name :

Bruton's tyrosine kinase

Critical for B-cell development and function.

Expected phenotype

Deficient B-cell function.

Human disease relevance

X-linked agammaglobulinemia, immunodeficiency.

Model applications

Immunodeficiency and B-cell pathway studies.

Keywords:

Immunodeficiency, B-cell development

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

BTK

conditional Knockout Mouse

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