Target

Gene symbol :  
Cblb
NCBI gene ID :  
12402
Gene full name :  
Casitas B-lineage lymphoma proto-oncogene-b
Synonym :  
Casitas B-lineage lymphoma proto-oncogene-b

Protein function

Protein name :  
Cbl-b
Involved in regulating immune response and T-cell activation.

Expected phenotype

Altered T-cell response.

Human disease relevance

Linked to autoimmune diseases and cancer.

Model applications

Autoimmunity and immune regulation research.

Keywords:

T-cell regulation, Immune response, Cancer

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Cblb

conditional Knockout Mouse

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