Hexb conditional Knockout mouse

Target

Gene symbol :

Hexb

NCBI gene ID :

15212

Gene full name :

Hexosaminidase B

Synonym :

Beta-hexosaminidase subunit beta

Protein function

Protein name :

HEXB

Enzyme that degrades GM2 gangliosides; deficiency leads to accumulation in lysosomes.

Expected phenotype

Neurological deterioration

Human disease relevance

Mutations cause Sandhoff disease, a lysosomal storage disorder.

Model applications

Models for lysosomal storage diseases and neurodegeneration.

Keywords:

Lysosomal Storage, Neurodegeneration, Sandhoff Disease

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Hexb

conditional Knockout mouse

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hPD-1 hLAG3

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hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.