Smad3 conditional Knockout mouse

Target

Gene symbol :

Smad3

NCBI gene ID :

17128

Gene full name :

SMAD family member 3

Synonym :

Mothers against decapentaplegic homolog 3, Mad3

Protein function

Protein name :

Mothers against decapentaplegic homolog 3

Regulates cell growth, differentiation, and apoptosis in TGF-beta signaling pathway.

Expected phenotype

Altered cell proliferation and tissue homeostasis.

Human disease relevance

Associated with cancer and fibrosis.

Model applications

TGF-beta signaling, cancer, and fibrosis research.

Keywords:

TGF-beta signaling, Cancer, Fibrosis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Smad3

conditional Knockout Mouse

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