Design of the genO-CT26-hCD39-LZ cell line
The genO-CT26-hCD39-LZ clonal cell line expresses high levels of a human/mouse chimeric CD39, and forms solid tumors in vivo. An optimized version of a luciferase-ZsGreen (LZ) fusion protein is also stably expressed for in vivo imaging and ex vivo tracking.
This cell line can be used in syngeneic models with our genO-hCD39 mouse model.
Features
- Express a functional chimeric CD39 with a fully humanized extracellular domain
- Express a luciferase-ZsGreen (LZ) fusion reporter
- Form solid tumors upon subcutaneous injection in fully immunocompetent mice
- Injected cells can be followed in vivo and ex vivo with our LZ reporter
Clients
