Target

Gene symbol :  
Vsig4
NCBI gene ID :  
27988
Gene full name :  
V-set and immunoglobulin domain containing 4
Synonym :  
V-set and immunoglobulin domain containing 4

Protein function

Protein name :  
VSIG4
Acts as a macrophage-specific complement receptor, modulating immune response.

Expected phenotype

Altered complement pathway response.

Human disease relevance

Related to autoimmune diseases and cancer.

Model applications

Autoimmune and macrophage function studies.

Keywords:

Autoimmunity, Immune modulation, Complement pathway

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Vsig4

conditional Knockout Mouse

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