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Applications of the hPD‑1 mouse model
Useful applications for researchers working on different biomedical fields, such as immuno-oncology, immuno-inflammation and autoimmunity:
- Assess the efficacy of PD-1-targeting compounds
- Perform tumor growth inhibition assays in the context of monotherapies or combotherapies
- Evaluate PD-1 agonists for the treatment of autoimmune and inflammatory conditions
- Gain insights into the mechanism of action (MOA) of diverse constructs and their potential therapeutic benefits
Features
- Physiological regulation and expression of a humanized PD-1
- Lack of expression of the murine target gene
- Fully functional mouse immune system
- Available on different genetic backgrounds C57BL/6 & BALB/c
Clients
- AbbVie (publication)
- Anaveon (poster, poster)
- AstraZeneca (publication)
- Bonum (poster)
- Charles River (poster, poster)
- CIDARA (poster)
- Janssen (publication)
- Reaction Biology (poster)
Clients
